Resistance to blood flow at maximal vasodilatation.

Letter to the Editor Resistance to Blood Flow at Maximal Vasodilatation

To THE EDITOR: In the April issue of Hypertension, a study by Distler's group (Schulte et al.), explored whether minimal forearm resistance to blood flow at maximal vasodilatation (R^J is elevated in human primary hypertension by repeating and critically extending the studies published in 1956 and 1958 by Folkow et al.In addition to the methods used by our group (ischemia, exercise, and local h...

Resistance to blood flow at maximal vasodilation.

Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1,000 words (typed double-spaced) in length and may be subject to editing or abridgment. Professor Folkow 1 questioned some of the methods used in our study 2 and cast doubts on our conclusions. We will comment here on the methodology only and leave it to the reader to draw conclusions from the data p...

Redistribution of cortical blood flow during renal vasodilatation in dogs.

Spreading vasodilatation in resistance arteries.

Focal application of vasodilators such as acetylcholine (ACh), which evoke arterial hyperpolarization, cause coordinated dilatation along the length of an artery with minimal decay with distance from the site of application. This phenomenon is called spreading vasodilatation. In an artery wall, the endothelium is separated from the surrounding smooth muscle cell layers by an internal elastic la...

Skeletal muscle vasodilatation during maximal exercise in health and disease.

Maximal exercise vasodilatation results from the balance between vasoconstricting and vasodilating signals combined with the vascular reactivity to these signals. During maximal exercise with a small muscle mass the skeletal muscle vascular bed is fully vasodilated. During maximal whole body exercise, however, vasodilatation is restrained by the sympathetic system. This is necessary to avoid hy...